Evolution after Gene Duplication
by Dittmar, Katharina; Liberles, DavidBuy New
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Summary
Author Biography
Katharina Dittmar de la Cruz holds both a Ph.D. in Molecular Parisitology and Entomology and a doctorate in Veterinary Medicine, both from the University of Leipzig, Germany.?An expert in phylogenetics, molecular evolution, and bioinformatics, she has recently turned her attention toward examining the implications of evolutionary forces on drug design.?Dr. Dittmar is an Assistant Professor at the SUNY University at Buffalo.
David Liberles earned his Ph.D. in Chemistry at the California Institute of Technology working on the biochemsitry of nucleic acids.?Subsequently, he has developed significant expertise in bioinformatics, computational biology and functional genomics.?His broad experience includes a professorship at the Stockholm Bioinformatics Center and consultancies with Novo Nordisk and other private research and diagnostic companies.?Currently he is Vice-Director of the University of Wyoming Bioinformatics Center and Assistant Professor of Molecular Biology.
Table of Contents
| Contributors | p. vii |
| Preface | p. xi |
| Understanding Gene Duplication Through Biochemistry and Population Genetics | p. 1 |
| Functional Divergence of Duplicated Genes | p. 23 |
| Duplicate Retention After Small- and Large-Scale Duplications | p. 31 |
| Gene Dosage and Duplication | p. 57 |
| Myths and Realities of Gene Duplication | p. 77 |
| Evolution After and Before Gene Duplication? | p. 105 |
| Protein Products of Tandem Gene Duplication: A Structural View | p. 133 |
| Statistical Methods for Detecting Functional Divergence of Gene Families | p. 163 |
| Mapping Gene Gains and Losses Among Metazoan Full Genomes Using an Integrated Phylogenetic Framework | p. 173 |
| Reconciling Phylogenetic Trees | p. 185 |
| On the Energy and Material Cost of Gene Duplication | p. 207 |
| Fate of a Duplicate in a Network Context | p. 215 |
| Evolutionary and Functional Aspects of Genetic Redundancy | p. 229 |
| Phylogenomic Approach to the Evolutionary Dynamics of Gene Duplication in Birds | p. 253 |
| Gene and Genome Duplications in Plants | p. 269 |
| Whole Genome Duplications and the Radiation of Vertebrates | p. 299 |
| Index | p. 313 |
| Table of Contents provided by Ingram. All Rights Reserved. |
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